Ibuprofen belongs to a group of medicines called NSAIDs. This makes it effective at relieving pain and reducing inflammation, but there is a risk of stomach-related side effects. It is considered a nonselective NSAID because it blocks both COX-2 enzymes (involved in pain signaling and inflammation) and COX-1 enzymes (associated with a protective effect on stomach lining). ![]() Ibuprofen (Advil) also blocks COX enzymes, but to a different extent than acetaminophen. Ibuprofen is a NSAID and relieves pain and fever and also reduces inflammation. Acetaminophen may be called paracetamol in some countries.Īdvil is a brand of ibuprofen. There are many different brands of acetaminophen in the U.S., examples include Aceta, Apra, and Mapap. Experts aren't sure exactly how acetaminophen (Tylenol) works but believe it affects COX enzymes in the brain, reducing the formation of prostaglandins (prostaglandins are substances released during injury that cause pain and inflammation). Acetaminophen relieves pain and also reduces fever.
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